Which of the following proteins plays a crucial role in the folding and quality control of newly synthesized proteins in the endoplasmic reticulum?

A Hsp70
B Hsp90
C BiP (Binding Immunoglobulin Protein) ✓
D TF (Transferrin)

Explanation

BiP is a molecular chaperone that plays a critical role in the folding and quality control of newly synthesized proteins in the endoplasmic reticulum, preventing protein misfolding and aggregation.

Source

Lodish et al., Molecular Cell Biology
Protein Metabolism Cell Biology Protein Quality Control Hard MEDICAL Confidence: high