What is the primary enzyme responsible for the degradation of dopamine in the brain, and its deficiency is associated with Parkinson's disease?

A Monoamine oxidase ✓
B Catechol-O-methyltransferase
C Dopamine beta-hydroxylase
D Tyrosine hydroxylase

Explanation

Monoamine oxidase is the primary enzyme responsible for the degradation of dopamine in the brain. A deficiency in this enzyme has been associated with Parkinson's disease.

Source

Biochemistry textbooks
Enzymes in Disease Biochemistry Neurotransmitter Metabolism Medium MEDICAL Confidence: high