Which of the following intermediates is a key regulator of the glycolytic pathway?

A Fructose-2,6-bisphosphate ✓
B Glucose-6-phosphate
C Pyruvate
D Acetyl-CoA

Explanation

Fructose-2,6-bisphosphate is a potent allosteric activator of the enzyme phosphofructokinase-1, which is a key regulatory step in the glycolytic pathway.

Source

Biochemistry research articles
Carbohydrate Metabolism Biochemistry Glycolysis Regulation Hard MEDICAL Confidence: high