Which of the following amino acids is associated with an increased risk of Homocysteinuria?

A Methionine ✓
B Phenylalanine
C Tyrosine
D Tryptophan

Explanation

Homocysteinuria is a genetic disorder caused by a deficiency of the enzyme cystathionine beta-synthase, which is involved in the metabolism of the amino acid methionine. Elevated levels of homocysteine in the blood can increase the risk of cardiovascular disease and other complications.

Mnemonic

Methionine = Meth-ilation error

Source

Harper's Illustrated Biochemistry
Metabolic and Nutritional Disorders Biochemistry Amino Acid Metabolism Medium MEDICAL Confidence: high