How does the enzyme acetylcholinesterase contribute to the pathogenesis of myasthenia gravis?

A It inhibits acetylcholine release
B It breaks down acetylcholine ✓
C It stimulates muscle contraction
D It regulates antibody production

Explanation

Acetylcholinesterase is an enzyme that breaks down acetylcholine, a neurotransmitter that stimulates muscle contraction. In myasthenia gravis, autoantibodies target acetylcholinesterase, leading to decreased acetylcholine breakdown and impaired muscle function.

Source

Harrison's Principles of Internal Medicine
Enzymes in Disease Neurology Neuromuscular Junction Disorders Hard MEDICAL Confidence: high