What is the role of the enzyme alpha-Galactosidase A in the human body, and its deficiency associated disease?

A Breaking down complex carbohydrates, and its deficiency leads to Cystic Fibrosis
B Breaking down fatty acids, and its deficiency leads to Fabry disease ✓
C Breaking down proteins, and its deficiency leads to Alzheimer's disease
D Breaking down nucleic acids, and its deficiency leads to Sickle Cell Anemia

Explanation

The enzyme alpha-Galactosidase A is involved in breaking down fatty acids, specifically globotriaosylceramide. Its deficiency leads to Fabry disease, a genetic disorder that results in the accumulation of this fatty substance in the body.

Mnemonic

Alpha-Gal = Alpha-Galactosidase, Fabry = Fatty Acid Breakdown

Source

NCBI Gene Review
Enzymes in Disease Biochemistry Lysosomal Storage Diseases Medium MEDICAL Confidence: high