What is the primary enzyme responsible for the breakdown of glycogen to glucose in the liver, and its deficiency leads to a rare genetic disorder called Hers disease?

A Glucokinase
B Debranching enzyme
C Glycogen phosphorylase ✓
D Phosphoglucomutase

Explanation

Glycogen phosphorylase is the primary enzyme involved in the breakdown of glycogen to glucose in the liver. Its deficiency leads to Hers disease, a rare genetic disorder.

Source

Harper's Illustrated Biochemistry
Enzymes in Disease Biochemistry Glycogen Metabolism Disorders Hard MEDICAL Confidence: high