Which enzyme is implicated in the development of Alzheimer's disease due to its role in beta-amyloid peptide production?

A Beta-secretase
B Gamma-secretase ✓
C Alpha-glucosidase
D Acetylcholinesterase

Explanation

Gamma-secretase is an enzyme complex involved in the cleavage of amyloid precursor protein, leading to the production of beta-amyloid peptides, which accumulate in the brains of Alzheimer's patients.

Source

Nature Reviews Neuroscience
Enzymes in Disease Neurobiology Neurodegenerative Disorders Hard MEDICAL Confidence: high