Which enzyme's deficiency leads to Gaucher's disease, characterized by the accumulation of glucocerebroside in cells?
Explanation
Gaucher's disease is a genetic disorder caused by a deficiency of the enzyme glucocerebrosidase. This enzyme is necessary for breaking down glucocerebroside, a type of lipid. Without it, glucocerebroside accumulates in cells, leading to various health issues.
Source
Genetics and Molecular Biology textbooks