What is the primary enzyme responsible for converting fructose-1,6-bisphosphate to fructose-6-phosphate in glycolysis?

A Aldolase
B Phosphofructokinase-1
C Fructose-1,6-bisphosphatase
D Glyceraldehyde-3-phosphate dehydrogenase
Fructose-1,6-bisphosphatase is the enzyme that catalyzes the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in the gluconeogenic pathway, but in glycolysis, the reverse reaction is catalyzed by Phosphofructokinase-1 and the forward reaction is not directly applicable. However, considering the closest relation and specific enzyme mentioned for the conversion in a broader context of glycolytic pathway regulation and its reverse reaction, Fructose-1,6-bisphosphatase is crucial for gluconeogenesis which shares many enzymes with glycolysis.
Lehninger Principles of Biochemistry
Carbohydrate Metabolism Biochemistry Glycolysis and Gluconeogenesis Medium MEDICAL Confidence: high