What is the role of enzyme alpha-galactosidase in the treatment of Fabry disease?

A It breaks down fatty acids
B It hydrolyzes globotriaosylceramide ✓
C It synthesizes glycoproteins
D It degrades glycogen

Explanation

Fabry disease is a genetic disorder caused by the deficiency of alpha-galactosidase, leading to the accumulation of globotriaosylceramide. The enzyme replacement therapy involves administering alpha-galactosidase to hydrolyze this lipid.

Source

NCBI Genetics Home Reference
Enzymes in Disease Biochemistry Lysosomal Storage Disorders Hard MEDICAL Confidence: high