Which of the following is a key regulator of fatty acid synthesis in the liver?

A Acetyl-CoA carboxylase ✓
B Carnitine palmitoyltransferase
C Fatty acid synthase
D HMG-CoA reductase

Explanation

Acetyl-CoA carboxylase is the rate-limiting enzyme in fatty acid synthesis, converting acetyl-CoA into malonyl-CoA, which is then used to synthesize fatty acids.

Mnemonic

_ACC = Acetyl-CoA Carboxylase = 'accelerator' of fatty acid synthesis

Source

Biochemistry by Stryer
Lipid Metabolism Biochemistry Fatty Acid Synthesis Hard NURSING Confidence: high