Which of the following is a key intermediate in the biosynthesis of cholesterol from acetyl-CoA?

A Mevalonate ✓
B HMG-CoA
C Isoprene
D Farnesyl pyrophosphate

Explanation

Mevalonate is a key intermediate in the biosynthesis of cholesterol from acetyl-CoA, as it is converted into isoprenoids, which are then used to synthesize cholesterol.

Mnemonic

Mevalonate = Me-val-on-ate, a key building block

Source

Biochemistry by Campbell and Farrell
Lipid Metabolism Biochemistry Cholesterol Biosynthesis Hard NURSING Confidence: high