Which enzyme's inhibition is a therapeutic strategy for the treatment of cystic fibrosis?

A Carbonic anhydrase
B Na+/K+-ATPase
C ENaC ✓
D Lactate dehydrogenase

Explanation

The inhibition of the epithelial sodium channel (ENaC) is a therapeutic strategy for the treatment of cystic fibrosis, as it helps to reduce sodium absorption and increase airway surface liquid.

Source

Nature Reviews Drug Discovery
Enzymes in Disease Molecular Biology Ion Channel Diseases Hard NURSING Confidence: medium