What is the primary enzyme responsible for the breakdown of acyl-CoA dehydrogenase in the diagnosis of medium-chain acyl-CoA dehydrogenase deficiency?

A Electron transfer flavoprotein
B Medium-chain acyl-CoA dehydrogenase ✓
C Very-long-chain acyl-CoA dehydrogenase
D Long-chain acyl-CoA dehydrogenase

Explanation

Medium-chain acyl-CoA dehydrogenase is the primary enzyme responsible for the breakdown of medium-chain fatty acids, and its deficiency leads to medium-chain acyl-CoA dehydrogenase deficiency.

Source

OMIM Database
Enzymes in Disease Biochemistry Fatty Acid Oxidation Disorders Hard NURSING Confidence: high