What is the primary cause of megaloblastic anemia in patients with metabolic disorders?

A Folate deficiency
B Vitamin B12 deficiency ✓
C Iron deficiency
D Vitamin C deficiency

Explanation

Vitamin B12 plays a crucial role in the production of red blood cells, and its deficiency can lead to megaloblastic anemia.

Mnemonic

B12 = Big 12 → essential for red blood cells

Source

Harper's Biochemistry
Metabolic and Nutritional Disorders Nutrition and Metabolism Vitamin Deficiencies Medium NURSING Confidence: high