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Human Blood Group System

The basis of human blood group system is the antigenic character of the Red cells. Red blood cell of the human being contains lipoprotein or glycoprotein on their surface which constitute the blood group antigens. About 300 blood group system so far discovered and some of the more common are____ Natural           : ABO (A, B) MNS (M, N, S,s) P (P­1, P, PK,P) Lewis (Lea, Leb) Luthern (Lua, Lub) Ii (I, i) etc. Immune          : Rhesus (C, c, D, d, E,e) Kidd (JKa, JKb) Duffy (Fya, Fyb) Kell (K, k, Kpa, kpb, Jsa, Jsb) etc. Of these only two blood group system ; ‘ABO’ and ‘Rhesus’ are of major clinical importance and constitute major antigens. Which causes serious complication in blood transfusion, hence they may be tested whenever blood is administrated. The other blood group systems are of less importance because the red cell antigens are weak and naturally occurring Read More